Grant Information

IMPLEMENTING TRANGENIC TOOLS TO PRODUCE COMMERCIAL SCION CULTIVARS RESISTANT TO HUANGLONGBING (HLB) AND CANKER

Sponsoring Institution Agricultural Research Service/USDA
Status ACTIVE
Funding Source USDA INHOUSE
Reporting Frequency Annual
Project Director STOVER E W
Accession Number 429471
Project Number 6034-21000-018-01R
Dates 2015-08-15 - 2018-08-14
Recipient Organization AGRICULTURAL RESEARCH SERVICE
219 SOUTH ROCK ROAD
FT PIERCE,FL 34945
Keywords (huanglongbing)
&
canker
citrus
development
diseases
foundation
hlb
proposal
research
transgenic
Research Effort Applied (50%)
Basic (50%)
Developmental (0%)
Classification Parameters
Knowledge AreaSubject of InvestigationField of SciencePercent
204 - Plant Product Quality and Utility (Preharvest) 920 - Orange 1080 - Genetics (excludes breeding) 40%
203 - Plant Biological Efficiency and Abiotic Stresses Affecting Plants 910 - Grapefruit 1000 - Biochemistry and biophysics 30%
212 - Pathogens and Nematodes Affecting Plants 999 - Citrus, general/other 1160 - Pathology 30%
Goals / Objectives
To produce citrus scion genotypes which are resistant to huanglongbing and citrus canker through use of transgenic approaches.
Methods (unparsed)

Novel opportunities to create improved citrus are being pursued through transgenic expression to yield Huanglongbing/Asian citrus psyllid (HLB/ACP)-resistance. Transgenic work using antimicrobial peptides (AMPs) continues apace with improved promoters and constructs: greatest promise is with chimeral peptides combining two antimicrobial peptides (AMPs), including citrus only genes. Transgenic hairpins will target key Asian citrus psyllid genes through double stranded Ribonucleic acid (dsRNA)- induced Ribonucleic acid interference (RNAi), which have shown efficacy against Asian citrus psyllid (ACP)and reductions in Liberibacter asiaticus (Las) transmission using citrus tristeza virus-inducted gene silencing (CTV- VIGS). Liberibacter asiaticus (Las)-focused constructs include FLS2 for host Liberibacter asiaticus recognition and genes up- regulated in tolerant citrus identified through Ribonucleic acid (RNAseq). Founder lines with an integration exchange platform have been developed in citrus, and function verified, to permit efficient construct variant comparison. Recent discovery of high efficiency phloem expression in citrus will be used to create constructs and use against huanglongbing. Plants were generated with 17 small chain variable fragment antibody (ScFv) targeting exterior epitopes of Liberibacter asiaticus, and require testing for huanglongbing and psyllid acquisition inhibition.